Erythropoietin in patients with traumatic brain injury and extracranial injury-A post hoc analysis of the erythropoietin traumatic brain injury trial.
Identifieur interne : 000D00 ( Main/Exploration ); précédent : 000C99; suivant : 000D01Erythropoietin in patients with traumatic brain injury and extracranial injury-A post hoc analysis of the erythropoietin traumatic brain injury trial.
Auteurs : Markus B. Skrifvars [Australie] ; Michael Bailey ; Craig French ; Jeffrey Presneill ; Alistair Nichol ; Lorraine Little ; Jacques Duranteau ; Olivier Huet ; Samir Haddad ; Yaseen Arabi ; Colin Mcarthur ; D James Cooper ; Rinaldo BellomoSource :
- The journal of trauma and acute care surgery [ 2163-0763 ] ; 2017.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Femelle, Humains, Lésions traumatiques de l'encéphale (mortalité), Lésions traumatiques de l'encéphale (traitement médicamenteux), Mâle, Polytraumatisme, Résultat thérapeutique, Score de gravité des lésions traumatiques, Échelle abrégée des traumatismes, Érythropoïétine (usage thérapeutique).
- MESH :
- mortalité : Lésions traumatiques de l'encéphale.
- traitement médicamenteux : Lésions traumatiques de l'encéphale.
- usage thérapeutique : Érythropoïétine.
- Adulte, Adulte d'âge moyen, Femelle, Humains, Mâle, Polytraumatisme, Résultat thérapeutique, Score de gravité des lésions traumatiques, Échelle abrégée des traumatismes.
English descriptors
- KwdEn :
- MESH :
- chemical , therapeutic use : Erythropoietin.
- drug therapy : Brain Injuries, Traumatic.
- mortality : Brain Injuries, Traumatic.
- Abbreviated Injury Scale, Adult, Female, Humans, Injury Severity Score, Male, Middle Aged, Multiple Trauma, Treatment Outcome.
Abstract
Erythropoietin (EPO) may reduce mortality after traumatic brain injury (TBI). Secondary brain injury is exacerbated by multiple trauma, and possibly modifiable by EPO. We hypothesized that EPO decreases mortality more in TBI patients with multiple trauma, than in patients with TBI alone.
DOI: 10.1097/TA.0000000000001594
PubMed: 28590358
Affiliations:
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Le document en format XML
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Skrifvars</name><affiliation wicri:level="1"><nlm:affiliation>From the Australian and New Zealand Intensive Care Research Centre (M.B.S., M.B., C.F., J.P., A.N., L.L., D.J.C., R.B.), School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia; Division of Intensive Care, Department of Anaesthesiology, Intensive Care and Pain Medicine (M.B.S.), University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Department of Intensive Care Helsinki, Finland; Department of Intensive Care (C.F.), Western Health; University of Melbourne (C.F.); Department of Intensive Care (J.P.), Royal Melbourne Hospital, Melbourne, Victoria, Australia; School of Medicine and Medical Sciences (A.N.), University College Dublin, Dublin, Ireland; Department of Intensive Care and Hyperbaric Medicine (A.N., D.J.C.), The Alfred, Melbourne, Victoria, Australia; Département d'Anesthésie-Réanimation (J.D.), Hôpital de Bicêtre, Assistance Publique des Hopitaux de Paris, Hôpitaux Universitaires Paris-Sud, Université Paris-Sud, Paris; Department of Anaesthesiology and Intensive Care Medicine (O.H.), CHU La Cavale Blanche, Brest, France; King Saud Bin Abdulaziz University for Health Sciences and King Abdullah International Medical Research Center (S.H., Y.A.), Riyadh, Saudi Arabia; Auckland City Hospital (C.M.), Auckland, New Zealand; and Department of Intensive Care (R.B.), Austin Health, Melbourne, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>From the Australian and New Zealand Intensive Care Research Centre (M.B.S., M.B., C.F., J.P., A.N., L.L., D.J.C., R.B.), School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia; Division of Intensive Care, Department of Anaesthesiology, Intensive Care and Pain Medicine (M.B.S.), University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Department of Intensive Care Helsinki, Finland; Department of Intensive Care (C.F.), Western Health; University of Melbourne (C.F.); 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Skrifvars</name><affiliation wicri:level="1"><nlm:affiliation>From the Australian and New Zealand Intensive Care Research Centre (M.B.S., M.B., C.F., J.P., A.N., L.L., D.J.C., R.B.), School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia; Division of Intensive Care, Department of Anaesthesiology, Intensive Care and Pain Medicine (M.B.S.), University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Department of Intensive Care Helsinki, Finland; Department of Intensive Care (C.F.), Western Health; University of Melbourne (C.F.); Department of Intensive Care (J.P.), Royal Melbourne Hospital, Melbourne, Victoria, Australia; School of Medicine and Medical Sciences (A.N.), University College Dublin, Dublin, Ireland; Department of Intensive Care and Hyperbaric Medicine (A.N., D.J.C.), The Alfred, Melbourne, Victoria, Australia; Département d'Anesthésie-Réanimation (J.D.), Hôpital de Bicêtre, Assistance Publique des Hopitaux de Paris, Hôpitaux Universitaires Paris-Sud, Université Paris-Sud, Paris; Department of Anaesthesiology and Intensive Care Medicine (O.H.), CHU La Cavale Blanche, Brest, France; King Saud Bin Abdulaziz University for Health Sciences and King Abdullah International Medical Research Center (S.H., Y.A.), Riyadh, Saudi Arabia; Auckland City Hospital (C.M.), Auckland, New Zealand; and Department of Intensive Care (R.B.), Austin Health, Melbourne, Victoria, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>From the Australian and New Zealand Intensive Care Research Centre (M.B.S., M.B., C.F., J.P., A.N., L.L., D.J.C., R.B.), School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia; Division of Intensive Care, Department of Anaesthesiology, Intensive Care and Pain Medicine (M.B.S.), University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Department of Intensive Care Helsinki, Finland; Department of Intensive Care (C.F.), Western Health; University of Melbourne (C.F.); Department of Intensive Care (J.P.), Royal Melbourne Hospital, Melbourne, Victoria, Australia; School of Medicine and Medical Sciences (A.N.), University College Dublin, Dublin, Ireland; Department of Intensive Care and Hyperbaric Medicine (A.N., D.J.C.), The Alfred, Melbourne, Victoria, Australia; Département d'Anesthésie-Réanimation (J.D.), Hôpital de Bicêtre, Assistance Publique des Hopitaux de Paris, Hôpitaux Universitaires Paris-Sud, Université Paris-Sud, Paris; Department of Anaesthesiology and Intensive Care Medicine (O.H.), CHU La Cavale Blanche, Brest, France; King Saud Bin Abdulaziz University for Health Sciences and King Abdullah International Medical Research Center (S.H., Y.A.), Riyadh, Saudi Arabia; Auckland City Hospital (C.M.), Auckland, New Zealand; and Department of Intensive Care (R.B.), Austin Health, Melbourne, Victoria</wicri:regionArea><wicri:noRegion>Victoria</wicri:noRegion></affiliation></author><author><name sortKey="Bailey, Michael" sort="Bailey, Michael" uniqKey="Bailey M" first="Michael" last="Bailey">Michael Bailey</name></author><author><name sortKey="French, Craig" sort="French, Craig" uniqKey="French C" first="Craig" last="French">Craig French</name></author><author><name sortKey="Presneill, Jeffrey" sort="Presneill, Jeffrey" uniqKey="Presneill J" first="Jeffrey" last="Presneill">Jeffrey Presneill</name></author><author><name sortKey="Nichol, Alistair" sort="Nichol, Alistair" uniqKey="Nichol A" first="Alistair" last="Nichol">Alistair Nichol</name></author><author><name sortKey="Little, Lorraine" sort="Little, Lorraine" uniqKey="Little L" first="Lorraine" last="Little">Lorraine Little</name></author><author><name sortKey="Duranteau, Jacques" sort="Duranteau, Jacques" uniqKey="Duranteau J" first="Jacques" last="Duranteau">Jacques Duranteau</name></author><author><name sortKey="Huet, Olivier" sort="Huet, Olivier" uniqKey="Huet O" first="Olivier" last="Huet">Olivier Huet</name></author><author><name sortKey="Haddad, Samir" sort="Haddad, Samir" uniqKey="Haddad S" first="Samir" last="Haddad">Samir Haddad</name></author><author><name sortKey="Arabi, Yaseen" sort="Arabi, Yaseen" uniqKey="Arabi Y" first="Yaseen" last="Arabi">Yaseen Arabi</name></author><author><name sortKey="Mcarthur, Colin" sort="Mcarthur, Colin" uniqKey="Mcarthur C" first="Colin" last="Mcarthur">Colin Mcarthur</name></author><author><name sortKey="Cooper, D James" sort="Cooper, D James" uniqKey="Cooper D" first="D James" last="Cooper">D James Cooper</name></author><author><name sortKey="Bellomo, Rinaldo" sort="Bellomo, Rinaldo" uniqKey="Bellomo R" first="Rinaldo" last="Bellomo">Rinaldo Bellomo</name></author></analytic><series><title level="j">The journal of trauma and acute care surgery</title><idno type="eISSN">2163-0763</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Abbreviated Injury Scale</term><term>Adult</term><term>Brain Injuries, Traumatic (drug therapy)</term><term>Brain Injuries, Traumatic (mortality)</term><term>Erythropoietin (therapeutic use)</term><term>Female</term><term>Humans</term><term>Injury Severity Score</term><term>Male</term><term>Middle Aged</term><term>Multiple Trauma</term><term>Treatment Outcome</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Femelle</term><term>Humains</term><term>Lésions traumatiques de l'encéphale (mortalité)</term><term>Lésions traumatiques de l'encéphale (traitement médicamenteux)</term><term>Mâle</term><term>Polytraumatisme</term><term>Résultat thérapeutique</term><term>Score de gravité des lésions traumatiques</term><term>Échelle abrégée des traumatismes</term><term>Érythropoïétine (usage thérapeutique)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Erythropoietin</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Brain Injuries, Traumatic</term></keywords><keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Brain Injuries, Traumatic</term></keywords><keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Lésions traumatiques de l'encéphale</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Lésions traumatiques de l'encéphale</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Érythropoïétine</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Abbreviated Injury Scale</term><term>Adult</term><term>Female</term><term>Humans</term><term>Injury Severity Score</term><term>Male</term><term>Middle Aged</term><term>Multiple Trauma</term><term>Treatment Outcome</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Femelle</term><term>Humains</term><term>Mâle</term><term>Polytraumatisme</term><term>Résultat thérapeutique</term><term>Score de gravité des lésions traumatiques</term><term>Échelle abrégée des traumatismes</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Erythropoietin (EPO) may reduce mortality after traumatic brain injury (TBI). Secondary brain injury is exacerbated by multiple trauma, and possibly modifiable by EPO. We hypothesized that EPO decreases mortality more in TBI patients with multiple trauma, than in patients with TBI alone.</div></front></TEI><affiliations><list><country><li>Australie</li></country></list><tree><noCountry><name sortKey="Arabi, Yaseen" sort="Arabi, Yaseen" uniqKey="Arabi Y" first="Yaseen" last="Arabi">Yaseen Arabi</name><name sortKey="Bailey, Michael" sort="Bailey, Michael" uniqKey="Bailey M" first="Michael" last="Bailey">Michael Bailey</name><name sortKey="Bellomo, Rinaldo" sort="Bellomo, Rinaldo" uniqKey="Bellomo R" first="Rinaldo" last="Bellomo">Rinaldo Bellomo</name><name sortKey="Cooper, D James" sort="Cooper, D James" uniqKey="Cooper D" first="D James" last="Cooper">D James Cooper</name><name sortKey="Duranteau, Jacques" sort="Duranteau, Jacques" uniqKey="Duranteau J" first="Jacques" last="Duranteau">Jacques Duranteau</name><name sortKey="French, Craig" sort="French, Craig" uniqKey="French C" first="Craig" last="French">Craig French</name><name sortKey="Haddad, Samir" sort="Haddad, Samir" uniqKey="Haddad S" first="Samir" last="Haddad">Samir Haddad</name><name sortKey="Huet, Olivier" sort="Huet, Olivier" uniqKey="Huet O" first="Olivier" last="Huet">Olivier Huet</name><name sortKey="Little, Lorraine" sort="Little, Lorraine" uniqKey="Little L" first="Lorraine" last="Little">Lorraine Little</name><name sortKey="Mcarthur, Colin" sort="Mcarthur, Colin" uniqKey="Mcarthur C" first="Colin" last="Mcarthur">Colin Mcarthur</name><name sortKey="Nichol, Alistair" sort="Nichol, Alistair" uniqKey="Nichol A" first="Alistair" last="Nichol">Alistair Nichol</name><name sortKey="Presneill, Jeffrey" sort="Presneill, Jeffrey" uniqKey="Presneill J" first="Jeffrey" last="Presneill">Jeffrey Presneill</name></noCountry><country name="Australie"><noRegion><name sortKey="Skrifvars, Markus B" sort="Skrifvars, Markus B" uniqKey="Skrifvars M" first="Markus B" last="Skrifvars">Markus B. 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